2009年8月22日 星期六

bisphosphonate for ONFH

published in JBJS Br, Aug 09

Alendronate
有些被用來治療ONFH

progression to collapse in 4 years
80% in control group
30% in intervention group

diagnosis of ONFH
l Predisposing factor of failure of THR or resurfacing

Early stage: better outcome

Stage III (collapse)
l Statistically significant better clinical function compared with control group
l Pain, disability, walking time, standing time

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